Fluorogenic probes to monitor cytosolic phospholipase A2 activity.
نویسندگان
چکیده
Arachidonic acid derivatives equipped with either one or two fluorescent groups attached to the tip of the alkyl chains were synthesized and shown to function as inhibitor and substrate probes of cPLA2. The inhibitor probe was demonstrated to perform dual functions of inhibition and imaging while the substrate probe could be used for activity assay.
منابع مشابه
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ورودعنوان ژورنال:
- Chemical communications
دوره 53 11 شماره
صفحات -
تاریخ انتشار 2017